Endocrine Abstracts

Background: Postpartum mood disturbances occur very often in otherwise healthy women, whereas thyroid function is affected during a normal pregnancy. We examined whether thyroid hormone levels in women free from thyroid dysfunction associate with the prevalence of postpartum mood disturbances.Methods: This cross-sectional study included 57 Greek women. Concentrations of thyroid hormones (free T3, free T4, TSH) and anti...

Aims: Lipoprotein(a) [Lp(a)] is an independent risk factor for atherosclerotic cardiovascular disease (ASCVD) in the general population. However, such a role in patients with familial hypercholesterolemia (FH) is less documented. The purpose of this study was to evaluate the association between Lp(a) concentrations and ASCVD prevalence in adult patients with FH.Methods: This was a cross-sectional study from the Hellenic Familial Hypercholesterolemia Regi...

Introduction: Polycystic Ovary Syndrome (PCOS) is the most common endocrinopathy in women. Studies exploring the experiences of people with PCOS reveal inadequate patient access to information and limited insight into healthcare professionals’ (HCP) attitudes regarding the condition. Simulation via Instant Messaging-Birmingham Advance (SIMBA) is a virtual simulation platform proven to increase learners’ confidence in their approach to simulated cases with a high acce...

Background: Adrenal incidentalomas (AI) are found in approximately 5% of the adult population. Most AIs are benign; however, small-scale studies have indicated that 20–50% of patients harbouring a benign AI show biochemical evidence of mild autonomous cortisol excess (MACE), previously termed subclinical Cushing’s syndrome. MACE is differentiated into MACE-1 (serum cortisol after overnight suppression with 1 mg dexamethasone (1 mg-DST) 50–140 nmol/l) and MACE-2 ...

Background: Adrenal incidentalomas (AI) are found in approximately 5% of the adult population. Most AIs are benign; however, small-scale studies have indicated that 20–50% of patients harbouring a benign AI show biochemical evidence of mild autonomous cortisol excess (MACE), previously termed subclinical Cushing’s syndrome. MACE is differentiated into MACE-1 (serum cortisol after overnight suppression with 1 mg dexamethasone (1 mg-DST) 50–140 nmol/l) and MACE-2 ...

Introduction: Educational interventions for healthcare professionals (HCPs) in diabetes and endocrinology often limits patient and public involvement (PPI). We studied the effectiveness of Simulation via Instant Messaging-Birmingham Advance (SIMBA) as a tool to improve knowledge about polycystic ovary syndrome (PCOS) in HCP and women with PCOS. Additionally, we aimed to identify and reduce gaps in knowledge and expectations between HCP and women living with PCOS.<p class="...

Background: Benign adrenal tumours (AT) can be non-functioning (NFAT) or associated with cortisol excess, as indicated by failure to suppress serum morning cortisol to <50 nmol/l in the 1mg-dexamethasone suppression test (1 mg-DST). The latter group divides into patients with clinically overt signs of cortisol excess (adrenal Cushing’s syndrome, CUSH) and patients lacking CUSH signs (mild autonomous cortisol excess, MACE). Smaller series and a recent meta-analysis rep...

Aims: Although rare, craniopharyngiomas are the commonest suprasellar tumour in childhood. Despite high overall survival, children and young people <19 years with craniopharyngiomas are at risk of multiple relapses and long-term tumour- and treatment-related morbidity. We sought to provide, for the first time, a national standard for best practice based on currently available evidence for the assessment, treatment and follow-up of paediatric craniopharyngiomas under the au...

BackgroundBenign adrenocortical tumours are found in 3–5% of adults and can be non-functioning (NFAT) or associated with cortisol excess. The latter group divides into patients with clinically overt signs (adrenal Cushing’s syndrome, CS) and patients lacking CS signs (mild autonomous cortisol excess, MACE). The 1 mg-overnight dexamethasone suppression test (DST) further differentiates MACE into MACE-1 (possible MACE; post-DST cortisol 50–1...

BackgroundPolycystic Ovary Syndrome (PCOS) is a common reproductive, endocrine and metabolic disorder. The UK National Institute of Health and Care Excellence (NICE) recommends evaluating emotional wellbeing in women with PCOS. Therefore, we conducted a health service evaluation to assess emotional wellbeing.MethodsWe invited women with PCOS via social media to complete an online survey in September 2020, sup...